Combination strategy targeting protein methylation may improve PARP inhibitor activity

Inherited mutations in BRCA genes cause defects in DNA damage repair pathways. Targeted therapy with PARP inhibitors – which block a DNA repair protein – is known to extend progression-free survival in patients with BRCA-mutant cancers, but many patients eventually develop resistance and have poor overall survival, underscoring a need to identify combination strategies that improve outcomes. Protein arginine methyltransferases (PRMTs), which regulate gene transcription and RNA splicing, are involved in many cancer-associated processes, leading Nidhi Sahni, Ph.D., and colleagues to...

Hugo Bellen named recipient of the 2024 Gruber Genetics Prize

The Gruber Foundation at Yale University has named eminent geneticist, Dr. Hugo Bellen, Distinguished Service Professor and March of Dimes Chair in Developmental Biology at Baylor College of Medicine and principal investigator at the Jan and Dan Duncan Neurological Research Institute (Duncan NRI) at Texas Children’s Hospital, as the recipient of the 2024 Gruber Genetics Prize. This prize honors Dr. Bellen’s varied and deeply impactful contributions to genetics research that range from identifying underlying mechanisms for many fundamental biological...

Memorial Hermann’s Amalia Maislos Stanton named to Becker’s 2023 ‘Chief Marketing Officers to Know’ List

Memorial Hermann Health System proudly announces that Amalia Maislos Stanton, senior vice president and chief strategic communications and marketing officer, has been named to Becker’s Healthcare Review’s list of ‘Chief Marketing Officers to Know’ for 2023.   According to Becker’s, the list recognizes bold strategic leaders who drive the planning and execution of marketing and communications initiatives that successfully position their hospitals and health systems as leaders within the market via brand development, data-backed marketing...

A new era of leadership: Community blood center welcomes new CEO

Gulf Coast Regional Blood Center is thrilled to announce the appointment of Nikhil Nayak as the organization’s new President and CEO. With over 25 years of distinguished experience in health and life sciences, Nikhil Nayak brings a wealth of expertise to lead the center into its next chapter of service and innovation.   Before joining Gulf Coast Regional Blood Center, Nikhil was the Chief Business Officer of San Diego Blood Bank, where he spearheaded their...

Houston Methodist Sugar Land Hospital welcomes OB-GYN Aliyya Childs, M.D.

Houston Methodist Sugar Land Hospital is pleased to welcome obstetrician/gynecologist Aliyya Childs, M.D., to Houston Methodist Obstetrics and Gynecology Associates at Sugar Land. She recently began seeing in Medical Office Building 2 on the Houston Methodist Sugar Land campus.   Childs specializes in abnormal uterine bleeding, adolescent and adult gynecology, comprehensive obstetrical care, contraception and family planning, health education, minimally invasive and robotic gynecologic surgeries, menopausal care, pelvic pain, uterine fibroid management, and well-women exams....

Houston Methodist Sugar Land Hospital welcomes cardiologist Gabriela M. Orgeron, M.D., FACC

Houston Methodist Sugar Land Hospital is pleased to welcome cardiologist Gabriela Orgeron, M.D., FACC, to Houston Methodist Cardiology Associates at Sugar Land. Dr. Orgeron is currently accepting new patients. Orgeron specializes in cholesterol disorders, echocardiography, heart failure, hypertension, nuclear cardiology, palpitations/arrhythmias, peripheral artery disease, prevention and treatment of coronary artery disease, valvular disease, and women’s cardiovascular disease. She is board-certified in internal medicine, cardiovascular disease, and nuclear cardiology.   “I am excited to join Houston...

Breast surgical oncologist joins Houston Methodist Clear Lake Hospital

Continuing to provide comprehensive, specialized health care to the local community, Houston Methodist Clear Lake Hospital this month welcomed breast surgical oncologist Michelino Scarlata, M.D. The addition of Scarlata means that breast cancer patients in Clear Lake and surrounding areas can receive specialized surgical techniques tailored to their individual needs without traveling far from home. Scarlata is a board-certified surgeon who is fellowship-trained in surgical oncology. He earned his medical degree from the University of Verona School of Medicine...

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