toto togel situs togel togel online toto togel situs slot link togel slot online togel online toto togel situs togel situs toto toto togel situs toto kawijitu situs toto kawijitu toto slot situs toto toto online situs slot situs toto slot gacor kawijitu slot thailand slot thailand toto slot rtp slot Post Views: 716
BY Michael R. Alexander, Esq., Brown & Fortunato, P.C. The passage of the One Big Beautiful Bill Act (OBBBA) marks one of the most sweeping changes to U.S. healthcare policy in decades. Signed into law on July 4, 2025, the bill introduces over $1 trillion in cuts to federal healthcare programs, reshaping Medicaid, Medicare, and ACA Marketplace coverage. Proponents of the law argue it is aimed at reducing waste and improving efficiency. But some of...
BY Tashiana Briggs, Partner – Tax, Healthcare and Professional Services, Adam Portacci, Director – Financial Advisory Health Care Valuation Services, and Josh Finrock, Director – Transfer Pricing, Weaver It appears the Grinch has stolen some of the jolly from the practice of medicine, with physicians facing a brutal reality: ever increasing clinical volume paired with declining margins. As a result, many practices are looking for ways to reduce cash outlays or show healthy income when...
BY Samuel Mathis MD Recently, my spouse and I welcomed our second child into the world. During this pregnancy, we followed all the recommended guidelines for healthy eating, physical activity, and preventative health. We also utilized some integrative therapies that were safe and proven to help improve the overall pregnancy experience. Physicians should have a base understanding of these therapies to engage with patients who are pregnant or hoping to become pregnant. One...
BY John Hawkins, President and CEO, THA After this year’s regular session of the Texas Legislature adjourned in June, I wrote that – in my experience, at least – there had never been a legislative session like it before. Now that we’re about to close the final chapter of 2025, I can safely apply that truth on a broader scale: for Texas hospitals, there’s never been a year like this before. From...
Zanidatamab, a bispecific HER2-targeted antibody, delivered clinically meaningful and durable responses for patients with HER2-positive biliary tract cancer (BTC), according to final results from the HERIZON-BTC-01 clinical trial. In this clinical trial, zanidatamab demonstrated an objective response rate of 41.3% and a median duration of response of 15.5 months, while patients whose tumors showed strongest levels of HER2 overexpression experienced even greater benefit – a 51.6% response rate and a median duration of response of 18.1 months Initial trial...
Researchers have identified a specific protein, RASH3D19, that is responsible for activation of RAS signaling pathways involved in aggressive tumor growth and resistance to KRAS inhibitors in patients with KRAS-mutant cancers. Blocking RASH3D19 in combination with KRAS inhibitors improved outcomes in preclinical models, suggesting this combination as a potential therapeutic strategy for patients with KRAS-mutant cancers. The study was led by Subrata Sen, Ph.D., deputy chair of Translational Molecular Pathology, and Hiroshi Katayama, Ph.D., associate professor of Translational Molecular...
Researchers have shown that DNA inflexibility, or rigidity, inside the nucleosome regulates the positioning of INO80. This highlights that the physical structure and shape of DNA, not just genetic information, are key components of DNA transcription. It also suggests that the Arp5 subunits may act as sensors that regulate INO80 remodeling depending on the shape of the DNA. The study was co-led by Blaine Bartholomew, Ph.D., professor of Epigenetics and Molecular Carcinogenesis, and colleagues Post Views: 258
Researchers discovered that renal medullary carcinoma (RMC) cells use an adaptive mechanism called “myeloid mimicry” to hide from the immune system and promote disease hyper progression after immunotherapy, highlighting specific targets that overcome treatment resistance in preclinical models. The study was led by Pavlos Msaouel, M.D., Ph.D., and Giannicola Genovese, M.D., Ph.D., both associate professors of Genitourinary Medical Oncology; Jianjun Gao, M.D., Ph.D., professor of Genitourinary Medical Oncology; and Linghua Wang, M.D., Ph.D., associate professor of Genomic Medicine, associate member of the James P....
Researchers have performed a comprehensive evaluation of five artificial intelligence (AI) models trained on genomic sequences, known as DNA language models. These comparisons provide valuable insights into their strengths and weaknesses and offer a framework for selecting appropriate models based on specific genomic tasks. The study was led by Chong Wu, Ph.D., assistant professor of Biostatistics and affiliate of the Institute for Data Science in Oncology; and Peng Wei, Ph.D., professor of Biostatistics. Post Views: 285
