Some patients with advanced colorectal cancer develop metastases in the lining of the abdominal cavity, known as peritoneal metastases. Cytoreductive surgery (CRS) can help remove most tumors, and it is sometimes combined with heated chemotherapy delivered to the abdominal cavity – a treatment approach called hyperthermic intraperitoneal chemotherapy (HIPEC) – to eliminate remaining cancer cells. In a retrospective study, researchers led by Michael White, M.D., and Paula Smith, M.D., examined the benefits of HIPEC in 147 patients with colorectal cancer and peritoneal metastases who received...

A major new study led by researchers at the University of Texas Medical Branch suggests that standard treatment for hypothyroidism may not fully protect patients from long-term risks such as dementia and premature death—even when thyroid-stimulating hormone (TSH) levels are within the normal range. The findings highlight potential benefits of combination therapy that includes both levothyroxine (T4) and liothyronine (T3).   Hypothyroidism is a common endocrine disorder in which the thyroid gland does not produce...