Erdafitinib demonstrates improved responses in FGFR-altered advanced urinary tract cancers

Targeted treatment with the fibroblast growth factor receptor (FGFR) inhibitor erdafitinib improved responses and overall survival compared to standard chemotherapy for patients with metastatic urothelial cancers with FGFR alterations. Researchers at The University of Texas MD Anderson Cancer Center led results from the Phase III THOR trial.   “Metastatic urothelial cancer continues to challenge us with its absence of a cure, highlighting the need for innovative treatment approaches,” said Arlene Siefker-Radtke, M.D., professor of Genitourinary Medical Oncology and senior investigator on the trial....

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