Validating immunogenic SARS-CoV-2 peptides for novel T cell therapeutic approaches

T cell responses against SARS-CoV-2 may provide durable protection against infections, and T cells targeting the virus may be useful for COVID-19 treatments. To best utilize T cells for prevention and treatment, it is critical to understand the viral targets, or peptides, that T cells recognize. To date, researchers have relied on in silico methods to predict immunogenic viral peptides, but little has been done to experimentally validate predicted targets. Researchers led by Ke Pan,...

CMS reminds hospitals of EMTALA obligations following passage of Texas Heartbeat Act

By Allison Shelton and Colleen Byrom, Brown and Fortunato On September 1, 2021, the highly debated Texas Heartbeat Act (“Heartbeat Act”) went into effect. In short, Texas’s new law prohibits a physician from knowingly performing or inducing an abortion if the physician has “detected a fetal heartbeat for the unborn child . . . or failed to perform a test to detect a fetal heartbeat,” and the abortion is not necessitated by a “medical emergency.”...

Serial radiation therapy is safe and effective as alternative treatment to systemic therapy for kidney cancer

In a new single-arm study, The University of Texas MD Anderson Cancer Center researchers reported that radiation therapy as monotherapy is a safe and effective non-invasive treatment for oligometastatic renal cell carcinoma (RCC). Led by Chad Tang, M.D., assistant professor of Radiation Oncology, the MD Anderson RCC Oligometastasis Phase II trial is the first study to investigate and report the use of stereotactic body radiation therapy (SBRT) as an alternative treatment to standard-of-care systemic therapy...

An employer’s preparedness for DOL audits could significantly mitigate exposure for wage and hour violations

By John Skousen, Partner, Fisher Phillips The U.S. Department of Labor (DOL) has the authority, through the Wage-Hour Division (WHD), to conduct inspections of workplaces and wage-hour audits.  DOL audits can lead to enforcement actions against employers found to be in violation of the Fair Labor Standards Act (FLSA), and related statutes governing wage payments.  The FLSA provides the WHD, through record audits and related inspections, to engage in “discovery” used to establish liability in...

PCAOB rule to determine auditors it cannot inspect is approved as SEC official stresses ability to inspect ‘completely’

The SEC issued an order approving a framework the PCAOB will use in determining registered accounting firms in a foreign location that the board is unable to inspect or investigate completely because of positions taken by local authorities. As part of its oversight activities, the SEC must sign off on any significant standards and rules the PCAOB adopts before they become effective. The rulemaking responds to the Holding Foreign Companies Accountable (HFCA) Act. During a...

Physical activity reduces risk of severe COVID symptoms and hospitalization

By Victor S. Sierpina, MD “Do or do not. There is no try.” -Yoda If there were a pill as good as physical activity, it would be a blockbuster. We have long known the benefits of exercise, as little as 150 minutes a week, on improving risk and outcomes of chronic diseases such as heart disease, diabetes, hypertension, and even cancer. Now, we can add our new buddy COVID-19 to the list. In a study...

More options, new savings: Get your patients covered now

By Ted Shaw, President/CEO, Texas Hospital Association Health care providers are in the best seat ever to encourage their patients to sign up now for health care coverage through the federal marketplace at HealthCare.Gov. Open enrollment began Nov. 1 for health plans for next year. With more options, new savings, and more time to get enrolled, the outlook has never been better to add Texans to the coverage rolls. Those who already have insurance through...

Houston Methodist Clear Lake Hospital is pleased to welcome Natasha Hirani, D.O., a board-certified medical oncologist, to its medical staff. Dr. Hirani joins Jitesh Joshi, M.D., at Houston Methodist Oncology Partners at Clear Lake, located in Suite 300 of Medical Office Building 2 on the hospital campus. Houston Methodist Oncology Partners is a QOPI® Certified Practice, awarded to providers that demonstrate defined quality and safety standards in the administration of cancer care. Dr. Hirani earned her...

Houston Methodist Sugar Land Hospital is pleased to welcome gastroenterologist Svetang Desai, M.D., who will begin seeing patients in December. Desai is joining Houston Methodist Gastroenterology Associates at Sugar Land, located in Medical Office Building 1, Suite 250 on the Houston Methodist Sugar Land campus. Desai earned his medical degree at the University of Tennessee, Health Science Center, in Memphis, Tennessee. He completed his internal medicine residency at Baylor College of Medicine in Houston, Texas....

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